Psoriatic Skin Disease Increases Risk for Uveitis
Psoriatic arthritis (PsA), the inflammatory arthritis that occurs with the chronic skin condition of psoriasis, is known to increase risk for other conditions including uveitis. However, the data on the risk for uveitis in patients with psoriatic arthritis are inconsistent, and even less evidence is available on the risk for uveitis in patients with psoriasis without arthritis. A recent study, published in JAMA Dermatology, examined the risk for new-onset uveitis in patients with mild psoriasis, severe psoriasis, and psoriatic arthritis and for the reverse relationship in patients with uveitis in a nationwide cohort of the Danish population.
The study found that there was an overall increased risk for uveitis in patients with psoriasis and psoriatic arthritis. The risk was higher for those with PsA. Similarly, the authors found an increased risk for mild psoriasis, severe psoriasis, and psoriatic arthritis in patients with uveitis. However, the overall incidence of psoriasis and psoriatic arthritis in patients with uveitis was low (n = 167), as was the incidence of uveitis in patients with psoriasis and psoriatic arthritis (n = 114). Nevertheless, the results remained consistent and indicated that patients with psoriatic skin disease, even in the absence of psoriatic arthritis, are at increased risk for uveitis and that the reverse relationship may also be of clinical importance.
The authors suggest that an “increased focus on eye symptoms in patients with psoriasis and psoriatic arthritis and on skin and joint symptoms in patients with uveitis may be appropriate.”
By: Wendy Meltzer, MPH
Adapted from the original article.
[image by Hamner Fotos]