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Live Blog: Product theater for Galderma: “Epiduo Forte Gel: A New Topical Treatment for Acne.” Faculty: Neal Bhatia, MD

In this live blog from the Annual Fall SDPA Conference in Orlando, FL, Neal Bhatia, MD, presented product theater for Galderma Laboratories called, “Epiduo Forte Gel: A New Topical Treatment for Acne.” Here are some of the highlights.

Dr. Bhatia spoke about Epiduo Forte Gel, (adapalene and benzoyl peroxide 0.3%/2.5%), a topical treatment for patients struggling with moderate to severe acne, presenting with comedonal, papulopustular, and nodulocystic lesions induced by inflammation.

Epiduo Forte Gel comes in a pump container. It is an enhanced product of the existing treatment by Galderma, Epiduo. Epiduo Forte Gel contains three times the concentration of the retinoid component found in previous formulations and also contains concentrated benzoyl peroxide.

Dr. Bhatia shared the findings from a study comparing a 12-week monotherapy treatment of Epiduo Forte Gel and a vehicle gel in patients with moderate to severe acne. The study showed that after 12-weeks 33.7% of patients experienced treatment success with Epiduo Forte Gel, while 11% of patients experienced treatment success with the vehicle.

The study also reported rates for patients who were classified as “severe” acne subjects who improved to a “mild” acne subject. After 12 weeks of treatment, 31.9% Epiduo Forte Gel “severe” subjects improved to “mild” versus 11.8% for the vehicle.

Dr. Bhatia stressed the 12-week Epiduo Forte Gel treatment time. Dr. Bhatia spoke on the challenges of working with patients’ impatience and self-consciousness. Often, patients want quick results, but Dr. Bahtia reminded us, “This is not a rash you’re treating, it’s a change in the architecture of your face that we want to see sustained after 12 weeks of treatment.”

Dr. Bhatia spoke on a patient’s difficulty in seeing the improvement that a successful acne treatment makes over time. Dr. Bhatia takes photographs of his patients so he is able to show the patient’s progress.

Dr. Bhatia shared that some adverse reactions to Epiduo Forte Gel were erythema, scaling, dryness, and stinging/burning and were mild to moderate in severity. Dr. Bhatia pointed out that adverse reactions commonly peaked at week 1 and showed a steady decrease for all the weeks after.

Further details on Epiduo Forte Gel can be found at

Image: Clint Mason

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