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Comedones

How to Manage Enlarged Pores

Enlarged facial pores, which sometimes appear as open comedones, are a pervasive cosmetic concern that impacts patient quality of life. They can be difficult to treat, in part due to lack of knowledge of the pathophysiology.

A recent study reviewed the currently proposed causes of enlarged pores and the treatments with therapeutic efficacy. Enlarged pore pathogenesis is complex, with the condition linked to multiples factors: seborrhea, loss of skin elasticity and tension, hair follicle size, genetic predisposition, acne, comedogenic xenobiotics, chronic photodamage, chronic radiodermatitis, and vitamin A deficiency.

Treatment options vary in effectiveness, but all primarily aim to decrease sebum production, rejuvenate skin, remove hair, and/or decrease follicular size. The authors state that both traditional topical treatment such as tretinoin, isotretinoin, and tazarotene, and newer botanically derived topical treatments show efficacy in reducing the size of facial pores and sebum production. Lasers, radiofrequency, and ultrasound devices are the most novel treatment and show efficacy, perhaps due to remodeling collagen fibers near pilosebaceous openings to increase skin elasticity and decrease sebum production.

After reviewing the available studies, the authors conclude that the reliability of available literature on efficacy of various treatments in diminishing facial skin pores has been challenging given that most studies are low in power, lack control groups, use non-uniform methods of reporting outcomes, and do not report complete adverse events.

 

Byline: Martha L. Sikes, MS, RPh, PA-C

Posted: November 9, 2016

Source: Cutis
Adapted from the original article.

[Image: Dermnet New Zealand]




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