Atopic Dermatitis Exposed | Video #3: IL-4 and IL-13, key Th2 cytokines, drive immune dysregulation in atopic dermatitis

Atopic Dermatitis Exposed | Video #3: IL-4 and IL-13, key Th2 cytokines, drive immune dysregulation in atopic dermatitis

 

“Th2 cells and their secreted cytokines are central to the pathophysiology of atopic dermatitis. In particular, Th2 cells produce interleukin-4 and interleukin-13, or IL-4 and IL-13, which are key drivers of the immune dysregulation that we see in atopic dermatitis.” Mark Boguniewicz, MD, discusses how IL-4 and IL-13, key Th2 cytokines, drive immune dysregulation in atopic dermatitis.

Dr. Boguniewicz is an allergy-immunology expert and professor of pediatrics in the Division of Allergy and Clinical Immunology at the National Jewish Health affiliate of University of Colorado School of Medicine in Denver, Colorado.

CLICK HERE | Learn more about the key Th2 cytokines in atopic dermatitis.

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References:
Bieber T. Atopic dermatitis. Ann Dermatol. 2010 May;22(2):125-137.

Noda S, Krueger JG, Guttman-Yassky E. The translational revolution and use of biologics in patients with inflammatory skin diseases. J Allergy Clin Immunol. 2015;135(2):324-336.

 

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