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Air Pollution and Increased Risk of Skin Aging

 

 

Evidence gathered from various studies show a correlation between high traffic-related airborn particule matter and risk of pigmentation spots and wrinkles.  

 

Air Pollution and Skin Aging

A study conducted with 400 German women between the ages of 70-80 tracked the effects of air pollution on the skin.  The amount of air pollution exposure was measured by the distance between the individual’s home and nearest roadway carrying over 10,000 vehicles per day. 

 

It was found that air pollution was related to an increase in facial wrinkles and pigmented spots. More than 20% of such spots were associated with an increase in particles and soot near the participant’s place of residence.  Background particle pollution not directly related to traffic particles also correlated to aging spots on the face. 

 

Through further animal and in-vitro human skin studies, doctors have found that these wrinkles form due to a degradation of collagen in the dermal matrix.  This happens when the polyaromatic hydrocarbons in traffic soot activate the aryl hydrocarbon receptors, increasing metalloproteinase-1 activity, which causes the collagen degradation.   Aryl hydrocarbon activation also catalyzes melanocyte multiplication, causing formation of pigmented aging spots.  There is hope that an aryl hydrocarbon receptor antagonist can be used on the skin to help prevent extraneous skin aging.

 

Beyond the Skin Effects 

Fine particulate polyaromatic hydrocarbons found in high-traffic areas have been shown to cause more than just adverse skin effects.

 

Type 2 Diabetes

The study discussed above also linked exposure to traffic-related air pollution with increased risk of type 2 diabetes.  Studies show that nanoparticles in traffic soot move from the upper respiratory track to the systemic circulation and cause inflammation in organs such as the pancreas.  1,775 healthy women (nondiabetic) between 54-55 years old participated in a study that took place between 1985 and 1994 in Germany.  The follow-up investigation was conducted in 2006.  Between 1990 and 2006, the study found 87 new cases of diabetes, and hazards for traffic-related exposure increased by 15-42%. Subclinical inflammation was associated with nanoparticle air pollution and was a strong predictor for the onset of diabetes.  Researchers found that women with more subclinical inflammation had a higher susceptibility for diabetes in relation to traffic-related particulate matter. 

 

Sources: Skin and Allergy News, Pub Med

[Image by Brett Weinstein]