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Acne Treatment Without Antibiotics

Dermatologists make up just 1% of all physicians but are responsible for almost 5% of antibiotic prescriptions. The primary use of antibiotics in dermatology practice is for the treatment of acne. Given the proliferation of antibiotic-resistant bacteria and the gravity of the consequences of this trend, a recent study suggests that dermatologists should maximize their use of non-antimicrobial therapy when treating acne. The authors conducted a detailed review of the literature and present data regarding the efficacy and appropriate use of non-antimicrobial treatments for acne. The authors examined 57 studies where treatment duration ranged from 6 weeks to 6 months. The majority of these studies included either patients with mild to moderate acne or those with moderate to severe acne.

The authors state that systemic antibiotics, when used as induction therapy for 3 months, are an appropriate component of treatment for moderate to severe acne patients. But after induction therapy, patients should be transitioned off of systemic antibiotics and onto a maintenance therapy regimen. Many non-antibiotic topical and systemic acne treatment options are available including: topical retinoids, BPO, combination products, azelaic acid, isotretinoin, subantimicrobial dosed antibiotics, hormonal therapies and physical modalities. The authors argue that these treatment options can be used in a step-wise manner depending on the disease severity, patient characteristics and patient’s therapeutic response.


Byline: Martha L. Sikes, MS, RPh, PA-C

Posted: September 26, 2017

Source: Springer Link
Adapted from the original article.

[Image: WikiMedia]

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